Skip to main content

Table 2 Univariate and multivariate cox regression (time to PSA failure) and bootstrapping analysis

From: Beyond D’Amico risk classes for predicting recurrence after external beam radiotherapy for prostate cancer: the Candiolo classifier

Variables Sub-groups Univariate analysis Multivariate analysis Bootstrapping
HR P value HR P value P value
Age ≥70 yy 0.85 0.001 0.89 0.019 0.16
<70 yy 1.18 1.12
PSA <7 0.52 <0.001 0.63 <0.001 <0.001
7-15 0.88 0.96
>15 2.17 1.65
Staging cT1 0.49 <0.001 0.77 <0.001 0.031
cT2 0.95 0.93
cT3-4 2.17 1.40
bGS ≤6 0.47 <0.001 0.59 <0.001 0.012
3 + 4 0.77 0.83
4 + 3 0.99 0.95
8 1.31 1.26
9-10 2.13 1.70
% Positive Cores 1-20 % 0.48 <0.001 0.67 <0.001 0.008
21-50 % 0.76 0.89
51-80 % 1.22 1.11
81-100 % 2.26 1.50
RT Dose Continuous 0.88 / Gy <0.001 0.89 / Gy <0.001 0.001
Therapy schedule RT alone 0.81 <0.001 1.25 <0.001 0.028
RT & ADT 1.24 0.80