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Table 2 Univariate and multivariate cox regression (time to PSA failure) and bootstrapping analysis

From: Beyond D’Amico risk classes for predicting recurrence after external beam radiotherapy for prostate cancer: the Candiolo classifier

Variables

Sub-groups

Univariate analysis

Multivariate analysis

Bootstrapping

HR

P value

HR

P value

P value

Age

≥70 yy

0.85

0.001

0.89

0.019

0.16

<70 yy

1.18

1.12

PSA

<7

0.52

<0.001

0.63

<0.001

<0.001

7-15

0.88

0.96

>15

2.17

1.65

Staging

cT1

0.49

<0.001

0.77

<0.001

0.031

cT2

0.95

0.93

cT3-4

2.17

1.40

bGS

≤6

0.47

<0.001

0.59

<0.001

0.012

3 + 4

0.77

0.83

4 + 3

0.99

0.95

8

1.31

1.26

9-10

2.13

1.70

% Positive Cores

1-20 %

0.48

<0.001

0.67

<0.001

0.008

21-50 %

0.76

0.89

51-80 %

1.22

1.11

81-100 %

2.26

1.50

RT Dose

Continuous

0.88 / Gy

<0.001

0.89 / Gy

<0.001

0.001

Therapy schedule

RT alone

0.81

<0.001

1.25

<0.001

0.028

RT & ADT

1.24

0.80