Table 1 Patient’s characteristics and baseline tumor features
Standard CRT | Extended CRT | p | ||
|---|---|---|---|---|
N | 99 | 12 | ||
Gender (M-F) | 47 – 52 (47.5 – 52.5) | 7 – 5 (58.3 – 41.7) | 0.48 | |
Age (years) | 60.3 ± 12.7 | 58.6 ± 8.4 | 0.53 | |
Tumor size (mm) | 43.2 ± 11.6 | 43.3 ± 6.5 | 0.96 | |
Distance anal verge (cm) | 3.9 ± 2.0 | 4.6 ± 1.3 | 0.13 | |
Initial Staging | ||||
cT | 2 | 6 (6.1 %) | 5 (41.7 %) | |
3 | 87 (87.9 %) | 7 (58.3 %) | ||
4 | 6 (6.1 %) | 0 (0.0 %) | 0.001 | |
cN | positive | 43 (43.4 %) | 8 (66.7 %) | 0.11 |
cUICC | I | 6 (6.1 %) | 3 (25.0 %) | |
II | 50 (50.5 %) | 1 (8.3 %) | ||
III | 43 (43.4 %) | 8 (66.7 %) | 0.006 | |
TRG 3 or 4 | 22 (30.1 %) | 3 (75.0 %) | 0.09 | |
CR (cCR or pCR) | 23 (23.2 %) | 8 (66.7 %) | 0.004 | |
Final tumor size (mm) | 40.6 ± 22.2 | 26.4 ± 7.9 | 0.01 | |
Final Staging | ||||
UICC | CCR | 16 (16.1 %) | 7 (58.4 %) | |
pCR | 7 (7.1 %) | 1 (8.3 %) | ||
I | 14 (14.1 %) | 1 (8.3 %) | ||
II | 30 (30.3 %) | 0 (0.0 %) | ||
III | 19 (19.2 %) | 2 (16.7 %) | 0.004 | |