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Table 2 Comparison of mean dose and biologically effective dose (using either α/β = 10 Gy (BED10) or 3 Gy (BED3) for tumor volumes and α/β = 3 Gy for all OARs) between sequential boost (SEQ) and the simultaneous integrated boost (SIB) schemes for all structures of the ten studied patients (mean ± SD)

From: Comparison of breast sequential and simultaneous integrated boost using the biologically effective dose volume histogram (BEDVH)

  SEQ SIB10 SIB3
Dose (Gy) BED10 (Gy10) BED3 (Gy3) Dose (Gy) BED10 (Gy10) Dose BED3 (Gy3)
PTVboost Prescription 66.0 79.2 110.0 64.4 79.2 62.9 110.0
PTVbreast Prescription 50.0 60.0 83.3 50.4 60.0 51.5 83.3
PTVboost 65.7 ± 0.7 78.7 ± 1.0 109.2 ± 1.7 64.2 ± 0.1 78.9 ± 0.1 62.6 ± 0.1 109.4 ± 0.3
PTVbreast 53.4 ± 0.7 63.8 ± 0.8 88.0 ± 1.0 52.2 ± 0.4 61.9 ± 0.6 52.8 ± 0.5 86.2 ± 1.0
ILung 9.0 ± 1.8 12.2 ± 2.7 8.2 ± 1.7 11.0 ± 2.5 8.2 ± 1.6 10.9 ± 2.4
CBreast 1.2 ± 0.4 1.3 ± 0.4 1.1 ± 0.3 1.2 ± 0.3 1.1 ± 0.2 1.2 ± 0.3
CLung 1.0 ± 0.3 1.0 ± 0.4 0.9 ± 0.2 0.9 ± 0.3 0.9 ± 0.2 0.9 ± 0.2
Heart (Lt.) 3.4 ± 0.7 3.9 ± 1.1 3.0 ± 0.9 3.5 ± 1.2 3.2 ± 0.7 3.6 ± 1.0
Heart (Rt.) 2.3 ± 0.5 2.4 ± 0.6 1.9 ± 0.2 2.0 ± 0.2 2.0 ± 0.6 2.1 ± 0.6