Table 7 Median and range of NTCP on lungpneumonitis grade ≥ 2 for peripheral and centrally-located tumor patients with three different sets of LKB model parameters and two different α/β ratios

Peripheral

0.7 (0.2, 5.3)

0.7 (0.1, 5.2)

0.01(-0.04,0.38)

30.5

1

0.3

Kwa [33]

Central

1.8 (0.2, 18.7)

1.7 (0.2, 18.5)

0.03(0.01,0.85)

Peripheral

2.5 (0.8, 6.0)

2.4 (0.8, 6.1)

0.04(-0.05,0.66)

30.8

0.99

0.37

Seppenwoolde [36] α/β = 1.3Gy [38]

Central

4.6 (0.9, 23.8)

4.4 (0.9, 23.6)

0.07(0.01,0.93)

Peripheral

2.1 (0.8, 5.8)

2.1 (0.7, 5.7)

0.03(-0.00,0.35)

30.8

0.99

0.37

Seppenwoolde [36] α/β = 3Gy

Central

3.1 (0.8, 13.9)

3.0 (0.8, 13.8)

0.04(0.01,0.47)

Peripheral

0.2 (0.0, 7.0)

0.2 (0.0, 15.9)

0.01(-0.12,1.10)

24.5

0.87

0.18

Burman [6]

Central

1.5 (0.0, 72.0)

1.2 (0.0, 71.2)

0.19(0.00,5.36)