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Table 6 Comparison of total physical doses totarget volume calculated using AAA and AXB for peripheral and centrally-located tumor patients

From: Radiobiological impact of dose calculation algorithms on biologically optimized IMRT lung stereotactic body radiation therapy plans

Tumor location

Target (dose metric)

Median dose (range) in Gy

P-values

  

AAA

AXB

 

peripheral

ITV (mean)

63.7 (62.3, 67.9)

63.9 (60.5, 68.1)

0.86

 

PTV (D95%)

60.0 (normalization)

58.3 (53.5,60.3)

4.66E-07

 

PTV (mean)

62.9 (61.7, 65.0)

62.2 (60.5, 64.5)

0.04

 

PTV (max)

66.0 (63.7, 73.2)

67.0 (64.1, 75.5)

0.19

 

PTV (min)

55.2 (51.2, 57.1)

51.3 (37.6, 56.1)

1.19E-05

Central

ITV (mean)

64.7 (63.6, 73.1)

64.1 (61.1, 69.3)

0.31

 

PTV (D95%)

60.0 (normalization)

59.0 (55.6, 59.4)

1.00E-4

 

PTV (mean)

63.5 (62.8, 67.2)

62.6 (61.0, 66.0)

0.04

 

PTV (max)

66.9 (64.8, 86.9)

67.5 (63.9, 84.4)

0.83

 

PTV (min)

53.1 (45.1, 57.0)

50.4 (42.3, 53.6)

0.06