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Table 3 Number of different breakpoints and physical length of chromosomes

From: Frequent induction of chromosomal aberrations in in vivo skin fibroblasts after allogeneic stem cell transplantation: hints to chromosomal instability after irradiation

Chromosome/chromosome arm

Physical length (Mb)

Prospective group

Retrospective group

before SCT

after 3 months

after 12 months

 

1p

128

1

10

5

23

1q

135

1

3

23

16

1

263 (8,0 %)

3

13 (5,8 %)

30 (12,7 %)

39 (10,3 %)

2p

99

-

10

5

12

2q

156

-

12

9

15

2

255 (7,7 %)

-

22 (9,9 %)

14 (5,9 %)

27 (7,1 %)

3p

99

-

9

9

10

3q

115

-

10

9

14

3

214 (6,5 %)

-

19 (8,5 %)

19 (8,1 %)

24 (6,3 %)

4p

56

-

-

7

4

4q

147

-

7

5

15

4

203 (6,2 %)

-

7 (3,1 %)

12 (5,1 %)

21 (5,5 %)

5p

52

-

1

5

4

5q

142

1

12

3

15

5

194 (5,9 %)

1

13 (5,8 %)

9 (3,8 %)

21 (5,5 %)

6p

65

-

6

6

14

6q

118

-

9

6

6

6

183 (5,6 %)

-

15 (6,7 %)

12 (5,1 %)

21 (5,5 %)

7p

65

-

9

4

5

7q

106

-

9

5

10

7

171 (5,2 %)

-

18 (8,1 %)

9 (3,8 %)

15 (4,0 %)

8p

50

-

3

1

8

8q

105

-

4

4

13

8

155 (4,7 %)

-

7 (3,1 %)

5 (3,4 %)

21 (5,5 %)

9p

51

-

6

2

3

9q

94

-

5

4

15

9

145 (4,4 %)

-

11 (4,9 %)

6 (2,6 %)

18 (4.7 %)

10p

44

-

2

6

5

10q

100

-

6

6

15

10

144 (4,4 %)

-

9 (4,0 %)

12 (5,1 %)

22 (5,8 %)

11p

58

-

5

3

2

11q

86

-

5

7

6

11

144 (4,4 %)

-

10 (4,5 %)

10 (4,2 %)

9 (2,4 %)

12p

39

-

4

2

3

12q

104

1

4

5

6

12

143 (4,3 %)

1

8 (3,6 %)

7 (2,9 %)

9 (2,4 %)

13p

16

-

-

1

3

13q

98

-

7

9

11

13

114 (3,5 %)

-

8 (3,6 %)

11 (4,7 %)

14 (3,7 %)

14p

16

-

1

1

-

14q

93

1

9

13

20

14

109 (3,3 %)

1

11 (6,3 %)

14 (5,9 %)

22 (5,8 %)

15p

17

-

2

4

6

15q

89

-

6

7

9

15

106 (3,2 %)

-

9 (6,7 %)

11 (4,7 %)

15 (3,9 %)

16

98 (3,0 %)

-

10 (4,5 %)

9 (3,8 %)

16 (4,2 %)

17

92 (2,8 %)

1

8 (3,6 %)

6 (2,6 %)

16 (4,2 %)

18

85 (2,6 %)

1

5 (2,2 %)

6 (2,6 %)

12 (3,2 %)

19

67 (2,0 %)

-

6 (2,7 %)

4 (1,7 %)

6 (2,4 %)

20

72 (2,2 %)

-

6 (2,7 %)

7 (3,0 %)

10 (2,6 %)

21

50 (1,5 %)

1

5 (2,3 %)

5 (2,1 %)

2 (0,5 %)

22

56 (1,7 %)

1

3 (1,4 %)

5 (2,1 %)

3 (0,8 %)

Xp

62 (1,9 %)

-

-

4

10

Xq

102 (3,1 %)

-

1

6

10

X

164 (5,0 %)

-

2 (0,9 %)

10 (4,3 %)

22 (5,8 %)

Y

59 (1,8 %)

-

1 (0,5 %)

1 (0,4 %)

-

Sum of breakpoints:

10

222

235

379

  1. Legend to Table 3: Physical length of chromosome arms is given in Mb = Megabases according to [28]. Distribution of breakpoints is shown for chromosome arms and for whole chromosomes. In a few cases (mainly due to derivative chromosomes), breakpoints could only be localized to a chromosome, but not to a certain chromosome arm. Distribution of the breakpoints on the shorter chromosomes 16–22 and Y (chromosome groups E-G) is only shown for the whole chromosome and not for chromosome arms