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Table 2 Dosimetric parameters of the treatment plans

From: Long-term results in malignant pleural mesothelioma treated with neoadjuvant chemotherapy, extrapleural pneumonectomy and intensity-modulated radiotherapy

 

Step & Shoot

Helical Tomotherapy

All Patients

41 patients

21 patients

62 patients

Mean value ± SD

Mean value ± SD

Mean value ± SD

Target volume (PTV)

 Mean Dose [Gy]

52.1 ± 2.3

53.5 ± 0.5

52.6 ± 2.0

 Standard Deviation [Gy]

3.5 ± 1.5

2.4 ± 1.2

3.1 ± 1.5

 V95% [%]

85.3 ± 5.3

92.3 ± 5.2

87.6 ± 6.2

 V90% [%]

93.3 ± 3.8

94.2 ± 3.9

94.2 ± 3.9

Contralateral Lung

 Mean Lung Dose [Gy]

7.6 ± 2.2

7.0 ± 1.2

7.4 ± 2.0

 V5Gy [%]

66.2 ± 23.0

71.5 ± 18.6

67.9 ± 21.6

 V20Gy [%]

1.7 ± 1.9

0.7 ± 1.3

1.4 ± 1.8

Liver (right-sided MPM)

 Mean Dose [Gy]

21.9 ± 3.9

26.4 ± 3.8

23.4 ± 4.4

 V30Gy [%]

24.7 ± 8.3

33.5 ± 7.8

27.5 ± 9.0

Liver (left-sided MPM)

 Mean Dose [Gy]

9.1 ± 2.3

10.4 ± 1.5

9.6 ± 2.1

 V30Gy [%]

2.0 ± 2.5

2.5 ± 2.7

2.2 ± 2.5

Heart

 V45Gy [%]

7.3 ± 7.5

12.4 ± 6.1

9.0 ± 7.4

Ipsilateral kidney

 Mean Dose [Gy]

9.9 ± 5.1

9.3 ± 2.5

9.7 ± 4.4

 V15Gy [%]

23.4 ± 23.2

16.5 ± 13.0

21.0 ± 20.4

Contralateral kidney

 Mean Dose [Gy]

3.1 ± 1.6

4.5 ± 1.5

3.6 ± 1.7

 V15Gy [%]

0.1 ± 0.2

0.3 ± 0.6

0.2 ± 0.4

Spinal Cord

 Maximum Dose [Gy]

36.0 ± 5.7

37.3 ± 5.3

36.4 ± 5.5

Esophagus

 V55Gy [%]

0.9 ± 1.7

2.2 ± 2.4

1.4 ± 2.1

  1. SD standard deviation, PTV planning target volume