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Table 3 Toxicity profile of chemoradiation with Cetuximab in all 21 patients

From: Prospective study of cetuximab and gemcitabine in combination with radiation therapy: feasibility and efficacy in locally advanced pancreatic head cancer

Toxicity Grade 1 Grade 2 Grade 3 Grade 4 All grades
  No. of events % No. of events % No. of events % No. of events % No. of events %
Hematologic           
 Anemia 10 47,6 6 28,6 0 0 0 0 16 76,2
 Leukopenia 2 9,5 5 23,8 8 38,1 2 9,5 17 80,9
 Granulocytopenia 5 23,8 8 38,1 4 19 1 4,8 18 85,7
 Thrombocytopenia 12 57,2 2 9,5 1 4,8 0 0 15 71,4
Constitutional           
 Fatigue 8 38,1 2 9,5 0 0 0 0 10 47,6
 Anorexia 1 4,8 1 4,8 0 0 0 0 2 9,5
Gastrointestinal           
 Nausea 7 33,3 3 14,3 0 0 0 0 10 47,6
 Vomiting 3 14,3 1 4,8 0 0 0 0 4 19
 Diarrhea 1 4,8 0 0 0 0 0 0 1 4,8
Liver and biliary           
 Elevated total bilirubin 1 4,8 1 4,8 0 0 0 0 2 9,5
 Elevated AST/ALT 6 28,6 3 14,3 0 0 0 0 9 4,3
 Elevated Alkaline phosphatase 5 23,8 3 14,3 1 4,8 0 0 9 4,3
 Elevated Gamma-GT 6 28,8 5 23,8 4 19 1 4,8 16 76,2
Acneiform Rash 3 14,3 3 14,3 0 0 0 0 6 28,8