Definitive radiotherapy alone over 60 Gy for patients unfit for combined treatment to stage II-III non-small cell lung cancer: retrospective analysis

Table 2 Univariate analysis of prognostic factors that influence PFS, CSS, and OS

Characteristics		PFS		CSS		OS
Characteristics	N	2-year rate	P-value	2-year rate	P-value	2-year rate	P-value
Age			0.62		0.43		0.58
<75	50	20		54		40
≥75	33	27		61		36
Sex			0.82		0.49		0.86
M	75	23		43		39
F	8	25		64		38
ECOG PS			0.53		0.28		0.20
0-1	43	23		59		44
2-3	40	23		53		33
^aFEV1(%)			0.84		0.96		0.69
≥70	45	22		50		47
<70	33	24		46		40
Pathology			0.81		0.92		0.71
Squamous cell carcinoma	62	24		60		63
Adenocarcinoma	13	23		35		23
Others	8	13		60		38
Tumor size			0.32		0.9		0.37
<7 c m	66	18		57		36
≥7 c m	17	41		55		47
T-stage			0.14		0.13		0.2
1-2	33	27		63		39
3-4	50	20		53		38
N-stage			0.55		0.67		0.55
0-1	27	30		64		44
2-3	56	20		53		36
Initial response			0.11		0.07		0.17
CR or PR	49	29		71		49
SD or PD	34	15		35		24

Abbreviations: PFS progession-free survival, CSS cause-specific survival, OS overall survival, ECOG PS Eastern Cooperative Oncology Group performance status, FEV1 forced expiratory volume in one second, CR complete response, PR partial response, SD stable disease, PD progressive disease
^aFEV1 test was not performed in 5 patients

ISSN: 1748-717X