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Table 2 Univariate analysis of prognostic factors that influence PFS, CSS, and OS

From: Definitive radiotherapy alone over 60 Gy for patients unfit for combined treatment to stage II-III non-small cell lung cancer: retrospective analysis

Characteristics   PFS CSS OS
N 2-year rate P-value 2-year rate P-value 2-year rate P-value
Age    0.62   0.43   0.58
 <75 50 20   54   40  
 ≥75 33 27   61   36  
Sex    0.82   0.49   0.86
 M 75 23   43   39  
 F 8 25   64   38  
ECOG PS    0.53   0.28   0.20
 0-1 43 23   59   44  
 2-3 40 23   53   33  
aFEV1(%)    0.84   0.96   0.69
 ≥70 45 22   50   47  
 <70 33 24   46   40  
Pathology    0.81   0.92   0.71
 Squamous cell carcinoma 62 24   60   63  
 Adenocarcinoma 13 23   35   23  
 Others 8 13   60   38  
Tumor size    0.32   0.9   0.37
 <7 c m 66 18   57   36  
 ≥7 c m 17 41   55   47  
T-stage    0.14   0.13   0.2
 1-2 33 27   63   39  
 3-4 50 20   53   38  
N-stage    0.55   0.67   0.55
 0-1 27 30   64   44  
 2-3 56 20   53   36  
Initial response    0.11   0.07   0.17
 CR or PR 49 29   71   49  
 SD or PD 34 15   35   24  
  1. Abbreviations: PFS progession-free survival, CSS cause-specific survival, OS overall survival, ECOG PS Eastern Cooperative Oncology Group performance status, FEV1 forced expiratory volume in one second, CR complete response, PR partial response, SD stable disease, PD progressive disease
  2. aFEV1 test was not performed in 5 patients
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