Table 3 Diagnostic performance of volume measurements for depicting local residual cervical tumor using MRI before treatment, at first and final BCT
Evaluation | AUC | Interclass coefficient (average) | Cut-off | Sensitivity and specificity | ||||
|---|---|---|---|---|---|---|---|---|
Observer 1 | Observer 2 | Observer 1 | Observer 2 | |||||
Sensitivity | Specificity | Sensitivity | Specificity | |||||
Absolute volume analysis (n:35) | ||||||||
(a) MRI before treatment | 0.60 (0.30–0.90) | 0.53 (0.29–0.78) | 0.98 (0.96–0.99) | 28,6 cm3 | 75 % (22–99) | 45 % (28–64) | 75 % (22–99) | 55 % (36–72) |
(b) MRI at the first BCT* | 0.91 (0.81–1.00) | 0.89 (0.78–1.00) | 0.95 (0.91–0.98) | 11,5 cm3 | 100 % (40–100) | 71 % (52–84) | 100 % (40–100) | 84 % (69–96) |
(c) MRI at the final BCT* | 0.98 (0.94–1.00) | 1.00 (1.00–1.00) | 0.94 (0.89–0.97) | 9,4 cm3 | 100 % (40–100) | 94 % (77–100) | 100 % (40–100) | 100 % (86–100) |
Volume regression analysis (n:35) | ||||||||
ΔVolume: First BCT MRI/MRI before treatment | 0.98 (0.93–1.00) | 0.89 (0.72–1.00) | 0.94 (0.87–0.97) | 69 % | 100 % (40–100) | 58 % (39–75) | 100 % (40–100) | 65 % (45–80) |
ΔVolume: Final BCT MRI/MRI before treatment* | 1.00 (1.00–1.00) | 1.00 (1.00–1.00) | 0.97 (0.95–0.99) | 77 % | 100 % (40–100) | 97 % (81–100) | 100 % (40–100) | 100 % (86–100) |