Table 3 Point scoring system of predictive factors and median overall survival by risk zones
Prognostic factor | Multivariable analysis hazard ratio (95 % CI) | Point score | |
|---|---|---|---|
KPS | |||
>80 | 1.00 | 0 | |
≤80 | 8.09 (3.79-17.28) | 4 | |
Extracranial disease | |||
absent | 1.00 | 0 | |
active/stable | 5.37 (1.65-17.48) | 3 | |
No. of lesions | |||
1 | 1.00 | 0 | |
2-4 | 2.61 (1.37-4.96) | 1.5 | |
>4 | 3.24 (1.56-6.72) | 2 | |
Gender | |||
Female | 1.00 | 0 | |
Male | 1.76 (1.04-2.97) | 1 | |
Risk zone | Point ranges | No. of patients (%) | Median OS, mo (95 % CI) |
Low | 0-3 | 15 (17.4) | not reached |
Moderate | 4-6 | 61 (71.7) | 7.60 (3.73-11.47) |
High | 6.5-10 | 10 (11.6) | 2.40 (1.79-3.01) |