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Table 5 Univariate and multivariate analysis for radiographic predictors of Local Control (LC) for CF-EBRT patients

From: Local Control Rates of Metastatic Renal Cell Carcinoma (RCC) to Thoracic, Abdominal, and Soft Tissue Lesions Using Stereotactic Body Radiotherapy (SBRT)

 

Univariate

Multivariate

Variable

P-value

HR (95 % CI)

P-value

Total Dose (Gy)

0.025*

0.994 (0.986 to 1.003)

0.216

Number of Fractions

0.114

0.872 (0.698 to 1.090)

0.232

Dose per Fractions (≥9 Gy)

0.950

0.729 (0.195 to 2.725)

0.640

BED (100 Gy)

0.017*

3.94 (0.028 to 2.345)

0.325

Site (Thorax vs Other)

0.867

1.579 (0.404 to 6.173)

0.513

Time from Primary Diagnosis

0.714

0.987 (0.961 to 1.015)

0.386

Male Gender

0.653

1.003 (0.244 to 4.128)

0.995

Age

0.560

0.953 (0.860 to 1.056)

0.366

Smoker

0.172

-

-

Greater than 5 Metastatic Lesions

0.933

0.886 (0.216 to 3.623)

0.867

Pre-Radiation Systemic Therapy

0.536

2.340 (0.586 to 9.345)

0.231

Post-Radiation Systemic Therapy

0.417

0.206 (0.035 to 1.242)

0.086

  1. BED biologic effective dose, HR hazard ration, CI confidence interval
  2. *-Statistically significant values