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Table 4 Univariate and multivariate analysis for radiographic predictors of Local Control (LC) for SBRT patients

From: Local Control Rates of Metastatic Renal Cell Carcinoma (RCC) to Thoracic, Abdominal, and Soft Tissue Lesions Using Stereotactic Body Radiotherapy (SBRT)

  Univariate Multivariate
Variable P-value HR (95 % CI) P-value
Total Dose (Gy) 0.772 0.999 (0.997 to 1.001) 0.608
Number of Fractions 0.789 1.086 (0.528 to 2.233) 0.822
Dose per Fractions (≥9 Gy) 0.474 0.835 (0.528 to 1.319) 0.442
BED (100 Gy) 0.534 0.988 (0.957 to 1.019) 0.461
Site (Thorax vs Other) 0.961 0.948 (0.915 to 1.012) 0.957
GTV 0.429 0.958 (0.921 to 1.091) 0.967
PTV 0.429 - -
Time from Primary Diagnosis 0.491 1.224 (0.645 to 2.320) 0.537
Age 0.701 1.063 (0.885 to 1.277) 0.513
Smoker 0.965 - -
Greater than 5 Metastatic Lesions 0.963 - -
Pre-Radiation Systemic Therapy 0.959 - -
Post-Radiation Systemic Therapy 0.961 - -
  1. BED biologic effective dose, GTV gross tumor volume, HR hazard ration, CI confidence interval