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Table 3 Univariate and multivariate analysis for radiographic predictors of Local Control (LC) for all patients

From: Local Control Rates of Metastatic Renal Cell Carcinoma (RCC) to Thoracic, Abdominal, and Soft Tissue Lesions Using Stereotactic Body Radiotherapy (SBRT)

 

Univariate

Multivariate

Variable

P-value

HR (95 % CI)

P-value

Total Dose (Gy)

0.001*

0.999 (0.998 to 1.001)

0.209

Number of Fractions

0.189

1.004 (0.849 to 1.185)

0.966

Dose per Fractions (≥9 Gy)

0.021

0.726 (0.469 to 1.124)

0.153

BED (100 Gy)

0.005*

0.264 (0.022 to 3.119)

0.293

Site (Thorax vs Other)

0.185

1.941 (0.515 to 7.323)

0.329

Time from Primary Diagnosis

0.318

0.996 (0.980 to 1.012)

0.663

Male Gender

0.048

0.481 (0.120 to 1.915)

0.301

Age

0.610

0.990 (0.916 to 1.071)

0.816

Smoker

0.123

0.276 (0.058 to 1.311)

0.107

Greater than 5 Metastatic Lesions

0.808

0.674 (0.170 to 2.673)

0.577

Pre-Radiation Systemic Therapy

0.517

2.299 (0.605 to 8.724)

0.223

Post-Radiation Systemic Therapy

0.332

0.201 (0.038 to 1.037)

0.056

  1. BED biologic effective dose, HR hazard ratio, CI confidence interval
  2. *-Statistically significant values