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Table 4 Conditional logistic regression analysis

From: Radiotherapy and subsequent thyroid cancer in German childhood cancer survivors: a nested case–control study

   Thyroid SN (17 cases, 34 controls) Any other neck SNs (8 HL, 1 NHL, 3 STS) (12 cases, 23 controls) Any neck SN (29 cases, 57 controls)
Model   Odds ratio/1 Gy 95 % CI Odds ratio/1 Gy 95 % CI Odds ratio/1 Gy 95 % CI
1 RT dose in region of SN (neck) 1.051 0.984-1.123 1.042 0.980-1.109 1.046 1.000-1.095
2 RT dose in region of SN (neck) 1.057 0.992-1.127 1.042 0.979-1.109 1.051 1.004-1.101
  RT dose in region of spine 1.080 0.994-1.173 0.995 0.931-1.063 1.031 0.985-1.079
3 RT dose in region of spine or neck 1.066 1.010-1.125 1.019 0.974-1.067 1.041 1.006-1.078
4 RT dose in region of SN (neck) 1.048 0.980-1.120 1.045 0.981-1.113 1.046 1.000-1.095
  Cumulative RT dose in other body regions 1.004 0.983-1.027 0.988 0.949-1.029 1.000 0.982-1.019
5 RT dose in region of SN (neck) 1.045 0.979-1.116 1.043 0.980-1.110 1.045 0.999-1.093
  Cumulative RT dose in adjacent body regionsa 1.009 0.986-1.034 0.994 0.948-1.042 1.006 0.986-1.027
  1. CI: confidence interval
  2. FN: first neoplasm
  3. Gy: Gray
  4. HL: Hodgkin’s Lymphoma
  5. ICCC: International Classification of Childhood Cancer
  6. NHL: Non-Hodgkin’s Lymphoma
  7. RT: radiotherapy
  8. SN: second neoplasm
  9. STS: Soft Tissue Sarcoma
  10. ahead, thorax, spine
  11. Results from conditional logistic regression analysis of effect of RT doses in the region of the neck, all other regions or at regions adjacent to the neck in 17 cases with SN of the thyroid and 12 cases of any other neck SN diagnosed 1980–2002 and 57 matched controls by FN (ICCC-3 classification [1]) diagnosed in 1980