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Table 1 Characteristics of cases with an SN in neck region by FN

From: Radiotherapy and subsequent thyroid cancer in German childhood cancer survivors: a nested case–control study

  

Thyroid SN

Any other neck SN (8 HL, 1 NHL, 3 STS)

ICCC group

First neoplasm type

Cases n

RT+ n

Median age at diagnosis of FN (range)

Median age at diagnosis of SN (range)

Median time interval FN to SN in years (range)

Cases n

RT+ n

Median age at diagnosis of FN (range)

Median age at diagnosis of SN (range)

Median time interval FN to SN in years (range)

I

Leukaemias

8

8

4.5 (1–14)

15.5 (8–30)

11.5 (7.4-16.6)

7

5

4 (2–13)

8(4–17)

4 (1.6-6.1)

II

Lymphomas

5

4

10 (7–13)

19 (14–25)

7.3 (4.0-17.6)

3

3

12 (8–14)

20 (18–24)

12.5 (4.2-12.9)

III

CNS tumours

2

2

3.5 (2–5)

13 (11–15)

9.1 (8.9-9.3)

0

-

-

-

-

IV

Neuroblastomas

0

-

-

-

-

1

0

0 (−)

4 (−)

3.6 (−)

VI

Renal tumours

1

1

3 (−)

12 (−)

8.5 (−)

1

1

0 (−)

15 (−)

14.5 (−)

IX

Soft tissue sarcomas

1

1

1 (−)

13 (−)

11.5 (−)

0

-

-

-

-

Total

All FN

17

16

5 (1–14)

15 (8–30)

9.3 (4.0-17.6)

12

9

4.5 (0–14)

12 (4–24)

4.3 (1.6-14.5)

  1. CNS: central nervous system
  2. FN: first neoplasm
  3. HL: Hodgkin’s Lymphoma
  4. ICCC: International Classification of Childhood Cancer
  5. NHL: Non-Hodgkin’s Lymphoma
  6. RT+: radiotherapy received
  7. SN: second neoplasm
  8. STS: Soft Tissue Sarcoma
  9. Characteristics of 17 cases with SN of the thyroid and 12 cases with any other neck SN diagnosed 1980–2002 by FN (ICCC-3 classification [1]) diagnosed in 1980–2000 in Germany, FN below the age of 15