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Table 1 Characteristics of cases with an SN in neck region by FN

From: Radiotherapy and subsequent thyroid cancer in German childhood cancer survivors: a nested case–control study

   Thyroid SN Any other neck SN (8 HL, 1 NHL, 3 STS)
ICCC group First neoplasm type Cases n RT+ n Median age at diagnosis of FN (range) Median age at diagnosis of SN (range) Median time interval FN to SN in years (range) Cases n RT+ n Median age at diagnosis of FN (range) Median age at diagnosis of SN (range) Median time interval FN to SN in years (range)
I Leukaemias 8 8 4.5 (1–14) 15.5 (8–30) 11.5 (7.4-16.6) 7 5 4 (2–13) 8(4–17) 4 (1.6-6.1)
II Lymphomas 5 4 10 (7–13) 19 (14–25) 7.3 (4.0-17.6) 3 3 12 (8–14) 20 (18–24) 12.5 (4.2-12.9)
III CNS tumours 2 2 3.5 (2–5) 13 (11–15) 9.1 (8.9-9.3) 0 - - - -
IV Neuroblastomas 0 - - - - 1 0 0 (−) 4 (−) 3.6 (−)
VI Renal tumours 1 1 3 (−) 12 (−) 8.5 (−) 1 1 0 (−) 15 (−) 14.5 (−)
IX Soft tissue sarcomas 1 1 1 (−) 13 (−) 11.5 (−) 0 - - - -
Total All FN 17 16 5 (1–14) 15 (8–30) 9.3 (4.0-17.6) 12 9 4.5 (0–14) 12 (4–24) 4.3 (1.6-14.5)
  1. CNS: central nervous system
  2. FN: first neoplasm
  3. HL: Hodgkin’s Lymphoma
  4. ICCC: International Classification of Childhood Cancer
  5. NHL: Non-Hodgkin’s Lymphoma
  6. RT+: radiotherapy received
  7. SN: second neoplasm
  8. STS: Soft Tissue Sarcoma
  9. Characteristics of 17 cases with SN of the thyroid and 12 cases with any other neck SN diagnosed 1980–2002 by FN (ICCC-3 classification [1]) diagnosed in 1980–2000 in Germany, FN below the age of 15