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Table 1 Mutations of known cancer genes in the glioblastoma SNB19 and the lung carcinoma A549 cell lines [30]

From: Simultaneous perturbation of the MAPK and the PI3K/mTOR pathways does not lead to increased radiosensitization

Cell line

Gene

Variant

Effect

SNB19

CDKN2A

Hom c.1_471 del 471, p.?

LOM

 

PTEN

Hom c.723_724insTT p.E242fsX15

LOM

 

TP53

Hom c.818G > A, p.R273H

LOM

A549

CDKN2A

Hom c.1_471 del 471, p.?

LOM

 

KRAS

Hom c.34G > A, p.G12S

LOM

 

STK11

Hom c.109C > T, p.Q37X

LOM

  1. Abbreviations: Hom homozygous, del deletion, LOM likely oncogenic mutation
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Radiation Oncology

ISSN: 1748-717X

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