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Table 3 Average patient percent relative reduction in dose parameters with DIBH compared to FB for left-sided breast cancer patients by treatment cohort. Significant p-values after adjusting for multiple testing are indicated by a double asterisk (**)

From: Cardiac dose reduction with deep inspiration breath hold for left-sided breast cancer radiotherapy patients with and without regional nodal irradiation

Parameter

WBRT

B/CWRT + RNI

p-value*

Dmean Heart

29.2 %

55.9 %

0.003**

Dmean LAD

43.5 %

72.1 %

0.014**

V20 Left Lung

8.9 %

6.6 %

0.305

  1. Wilcoxon sum-rank test used in for comparison of all variables*In this group, to achieve significance p-values must be < 0.0167 to account for multiple testing. **Indicates significance when compared to the Bonferroni adjusted criterion