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Fig. 4 | Radiation Oncology

Fig. 4

From: An expression analysis of markers of radiation-induced skin fibrosis and angiogenesis in wound healing disorders of the head and neck

Fig. 4

Boxplot diagrams visualizing the gene expression data of the investigated genes α-Procollagen: a: patients with (n = 18) and without (n = 31) a history of Radiation Therapy (RT); b: patients with (n = 15) and without (n = 22) occurrence of postoperative Wound Healing Disorders (WHD). VWF: c: patients with (n = 9) and without (n = 35) a history of RT; d: patients with (n = 10) and without (n = 18) occurrence of WHD. TGF-β1: e: patients with (n = 18) and without (n = 29) a history of RT; f: patients with (n = 15) and without (n = 22) occurrence of WHD. Measured by real-time RT-PCR in cervical tissue samples. Given is the median value, (with the 75th percentile and the 25th percentile). The range is shown as a vertical line; extreme values are excluded. P-values were calculated by mean of the Mann–Whitney test. Statistical significance between groups could be shown (all *: p < 0.005). WHD = wound healing disorder

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