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Table 3 System performance evaluation

From: Normal tissue complication probability modeling for cochlea constraints to avoid causing tinnitus after head-and-neck intensity-modulated radiation therapy

  Logistic NTCP LKB NTCP
AUC 0.76 (0.69–0.84) 0.76 (0.69–0.84)
Brier (scaled) 0.16 0.16
Omnibus P < 0.001 P < 0.001
HL test (p-value) 0.82 0.43
NPV-TD 50 0.90 0.90
NPV-TD 20 0.92 0.92
AIC 257.79 259.48
  1. Abbreviation: NTCP normal tissue complication probability, LKB Lyman-Kutcher-Burman, NPV Negative predictive value, AUC Area under the receiver operating characteristic curve, HL Hosmer–Lemeshow test, NPV negative predictive value, TD 50 the dose predicting a 50 % risk of complications, TD 20 the dose predicting a 20 % risk of complications, AIC Akaike’s information criterion
  2. Bin sizes used for Hosmer–Lemeshow test were 15<, 15–25, 25–35, 35–45, >45 Gy (five bins)