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Table 3 System performance evaluation

From: Normal tissue complication probability modeling for cochlea constraints to avoid causing tinnitus after head-and-neck intensity-modulated radiation therapy

 

Logistic NTCP

LKB NTCP

AUC

0.76 (0.69–0.84)

0.76 (0.69–0.84)

Brier (scaled)

0.16

0.16

Omnibus

P < 0.001

P < 0.001

HL test (p-value)

0.82

0.43

NPV-TD 50

0.90

0.90

NPV-TD 20

0.92

0.92

AIC

257.79

259.48

  1. Abbreviation: NTCP normal tissue complication probability, LKB Lyman-Kutcher-Burman, NPV Negative predictive value, AUC Area under the receiver operating characteristic curve, HL Hosmer–Lemeshow test, NPV negative predictive value, TD 50 the dose predicting a 50 % risk of complications, TD 20 the dose predicting a 20 % risk of complications, AIC Akaike’s information criterion
  2. Bin sizes used for Hosmer–Lemeshow test were 15<, 15–25, 25–35, 35–45, >45 Gy (five bins)