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Table 1 Characteristics of patients with head and neck cancer

From: Normal tissue complication probability modeling for cochlea constraints to avoid causing tinnitus after head-and-neck intensity-modulated radiation therapy

  Value—x (%)
HNC (n = 422)
Age (y)
 Mean 50
 Range 26–73
Gender (n)
 Male 381 (90.3 %)
 Female 41 (9.7 %)
Tumor site
 Larynx 48 (11.4 %)
 Hypopharynx 68 (16.1 %)
 Oropharynx 54 (12.8 %)
 Oral cavity 102 (24.2 %)
 Nasopharyngeal carcinoma 150 (35.5 %)
AJCC stage
 I 0
 II 34 (8.1 %)
 III 95 (22.5 %)
 IV 293 (69.4 %)
Cochlea mean dose
 1–10 43 (10.2 %)
 10–20 118 (28 %)
 20–30 139 (32.9 %)
 30–40 101 (23.9 %)
 40–50 15 (3.6 %)
 50–60 6 (1.4 %)
Tinnitus (grade 2+)
 Yes 49 (11.6 %)
 No 373 (88.4 %)
Cochlea mean dose Gy (range) 23.72 (1.73–58.83)
 Without grade 2 + Tinnitus 22.44 (1.73–50.26)
 With grade 2 + Tinnitus 33.46 (8.72–58.83)
Chemotherapy  
 Yes 150 (35.5 %)
 No 272 (64.5 %)
  1. Abbreviation: AJCC American Joint Committee on Cancer, HNC head and neck cancer