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Table 1 Characteristics of patients with head and neck cancer

From: Normal tissue complication probability modeling for cochlea constraints to avoid causing tinnitus after head-and-neck intensity-modulated radiation therapy

 

Value—x (%)

HNC (n = 422)

Age (y)

 Mean

50

 Range

26–73

Gender (n)

 Male

381 (90.3 %)

 Female

41 (9.7 %)

Tumor site

 Larynx

48 (11.4 %)

 Hypopharynx

68 (16.1 %)

 Oropharynx

54 (12.8 %)

 Oral cavity

102 (24.2 %)

 Nasopharyngeal carcinoma

150 (35.5 %)

AJCC stage

 I

0

 II

34 (8.1 %)

 III

95 (22.5 %)

 IV

293 (69.4 %)

Cochlea mean dose

 1–10

43 (10.2 %)

 10–20

118 (28 %)

 20–30

139 (32.9 %)

 30–40

101 (23.9 %)

 40–50

15 (3.6 %)

 50–60

6 (1.4 %)

Tinnitus (grade 2+)

 Yes

49 (11.6 %)

 No

373 (88.4 %)

Cochlea mean dose Gy (range)

23.72 (1.73–58.83)

 Without grade 2 + Tinnitus

22.44 (1.73–50.26)

 With grade 2 + Tinnitus

33.46 (8.72–58.83)

Chemotherapy

 

 Yes

150 (35.5 %)

 No

272 (64.5 %)

  1. Abbreviation: AJCC American Joint Committee on Cancer, HNC head and neck cancer