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Table 4 Dosimetric changes in OARs

From: Determining appropriate timing of adaptive radiation therapy for nasopharyngeal carcinoma during intensity-modulated radiation therapy

OARs

Parameter

Plan-0

Plan-1

Plan-2

Plan-3

Plan-4

Plan-5

BT

Dmax (Gy)

53.21 ± 3.51

53.48 ± 4.59

53.51 ± 3.87

55.19 ± 3.40

55.84 ± 3.12

56.54 ± 3.72

P value

 

0.613

0.590

<0.001

<0.001

<0.001

SC

Dmax (Gy)

40.74 ± 3.22

41.34 ± 3.36

43.08 ± 6.27

42.84 ± 5.72

42.66 ± 4.88

42.24 ± 3.87

P value

 

0.017

0.041

0.030

0.012

0.001

PG-Lt

Dmean (Gy)

34.31 ± 5.53

34.33 ± 5.58

35.23 ± 6.07

36.72 ± 6.67

37.17 ± 7.47

37.40 ± 7.62

P value

 

0.990

0.421

0.031

0.027

0.020

V30 (%)

47.08 ± 2.06

47.57 ± 2.95

50.35 ± 5.00

52.38 ± 3.93

51.33 ± 4.05

53.37 ± 4.72

P value

 

0.773

0.229

0.017

0.063

0.010

PG-Rt

Dmean (Gy)

32.98 ± 3.58

33.31 ± 4.88

33.44 ± 4.61

34.69 ± 5.02

35.40 ± 3.93

38.58 ± 1.07

P value

 

0.673

0.533

0.083

0.003

0.038

V30 (%)

43.72 ± 6.49

44.79 ± 9.94

45.19 ± 9.16

48.34 ± 0.86

50.10 ± 8.51

51.61 ± 0.05

P value

 

0.499

0.298

0.051

0.002

0.001

Glottis

Dmean (Gy)

40.97 ± 7.27

41.42 ± 7.67

41.51 ± 7.60

41.72 ± 7.46

41.45 ± 7.46

42.61 ± 9.69

 

P value

 

0.167

0.062

0.035

0.100

0.137

Eye-Rt

Dmax (Gy)

27.55 ± 8.34

30.30 ± 8.33

28.48 ± 8.30

30.20 ± 8.88

30.14 ± 9.45

29.79 ± 0.25

 

P value

 

0.057

0.321

0.014

0.016

0.090

Lens-Lt

Dmax (Gy)

6.87 ± 1.50

8.35 ± 3.40

8.04 ± 3.01

8.41 ± 3.27

8.56 ± 2.83

8.60 ± 3.91

 

P value

 

0.046

0.035

0.041

0.008

0.082

  1. OARs organs at risk, BT brain stem, SC spinal cord, PG-Lt left parotid gland, PG-Rt right parotid gland, Eye-Rt right eye, Lens-Lt left lens