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Table 1 Dosimetric parameters

From: Dosimetric comparison of carbon ion radiotherapy and stereotactic body radiotherapy with photon beams for the treatment of hepatocellular carcinoma

 

Carbon ion radiotherapy

SBRT with photons

P value

PTV D90

59.6 ± 0.2 (GyRBE)

56.6 ± 0.3 (Gy)

p < 0.05

HI

1.19 ± 0.03

1.21 ± 0.01

p = 0.61

CI

0.79 ± 0.06

0.37 ± 0.02

p < 0.05

Mean liver dose

8.1 ± 1.4 (GyRBE)

16.1 ± 2.5 (Gy)

p < 0.05

Liver V5

20.2 ± 3.2 %

53.8 ± 7.2 %

p < 0.05

Liver V20

14.2 ± 2.5 %

31.5 ± 6.2 %

p < 0.05

Liver V30

11.6 ± 2.3 %

19.7 ± 4.1 %

p = 0.11

Liver V50

8.5 ± 1.8 %

9.7 ± 2.1 %

p = 0.67

D max of GI tract

8.4 ± 4.3 (GyRBE)

17.4 ± 7.1 (Gy)

p = 0.29

  1. Abbreviations: PTV D90 Minimum dose covering the 90 % of planning target volume, HI Homogeneity index, CI Conformity index, V5-50 Volume of liver received more than 5 Gy to 50 Gy, GI tract Gastrointestinal tract