Table 2 Canine GI toxicity rates from studies using hypofractionated radiotherapy
From: Late gastrointestinal tissue effects after hypofractionated radiation therapy of the pancreas
Author (reference) | Nc | Median follow-Up (months) | Radiotherapy | EQD 1.84 | Chemo (%) | Surgery (%) | Late GI complications | Complication rate | Total GI toxicity rate |
|---|---|---|---|---|---|---|---|---|---|
Ahmadu-Suka et al. [23] | 4 | 4.8 | 17.5 Gy 1 fxa + 50 Gyb (exact) | 126 | none | 100 % | 0/4 (0 %) | 0 % | |
3 | 25 Gy 1 fxa + 50 Gyb (exact) | 177 | none | 100 % | 0/3 (0 % | 0 % | |||
4 | 32.5 Gy 1 fxa + 50 Gyb (exact) | 256 | none | 100 % | Non-perforated duodenal ulcersd | 3/4 (75 %) | 100 % | ||
Perforated ulcersd | 1/4 (25 %) | ||||||||
4 | 40 Gy 1 fxa + 50 Gyb (exact) | 355 | none | 100 % | Non-perforated duodenal ulcersd | 1/4 (25 %) | 100 % | ||
Perforated ulcersd | 3/4 (75 %) | ||||||||
Halberg et al. [24] | 2 | 6 | 30 Gy 1 fxa (exact) | 176 | none | 100 % | Duodenal ulceration, grade 3 | 2/2 (100 %) | 100 % |