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Table 2 IMRT vs. 3D-CRT: PTV based dosimetric parameters of all 41 patients

From: Dose distribution and tumor control probability in out-of-field lymph node stations in intensity modulated radiotherapy (IMRT) vs 3D-conformal radiotherapy (3D-CRT) of non-small-cell lung cancer: an in silico analysis

 

IMRT

3D-CRT

p

PTV, cm3

433.3 ± 168.8

 

Total dose (Dref)

   

 Median (range), Gy

72 (62–110)

70 (58–100)

 

 Mean ± SD, Gy

74.3 ± 9.1

70.1 ± 7.9

<0.00001

 ≥60 Gy, no. (%)

41 (100)

40 (98)

 

 ≥66 Gy, no. (%)

39 (95)

32 (78)

 

Dmean-PTV, Gy ± SD

73.6 ± 9.0

70.0 ± 8.1

<0.00001

D90-PTV, Gy ± SD

71.3 ± 9.0

66.9 ± 7.8

<0.00001

CI ± SD

0.79 ± 0.04

0.50 ± 0.10

<0.00001

  1. IMRT intensity modulated radiotherapy, 3D-CRT 3D-conformal radiotherapy, PTV planning target volume, D ref prescribed reference dose, SD standard deviation, D mean mean dose in predefined region of interest, D 90 dose, administered to 90 % of region of interest, CI conformal index