Fig. 1
From: Next-generation sequencing: hype and hope for development of personalized radiation therapy?
Genetic heterogeneity of squamous cell carcinomas of the head and neck region (HNSCC). The relative distribution of genes affected by mutations is shown according to their mean prevalence within the three analyzed study cohorts (≤3 % vs. >3 % of cases) and their frequency of occurrence at hotspot regions and/or recurrent base positions. The results shown here are based upon somatic mutation data generated by the TCGA Research Network [60], Stransky et al. [59] and Agrawal et al. [58]