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Table 7 Correlation of manometrical findings with EORTC QLQ-CR38 scores

From: Long-term effects of neoadjuvant chemoradiotherapy followed by sphincter-preserving resection on anal sphincter function in relation to quality of life among locally advanced rectal cancer patients: a cross-sectional analysis

 

Manometrical findings

 

Resting pressure (mmHg)

MSP (mmHg)

RST volume (mL)

MBDV causing RAIR (mL)

EORTC QLQ-CR38 components

r

p

r

p

r

p

r

p

Functional scales

 Body image (n = 26)

0.435

0.030

0.160

0.435

−0.173

0.420

0.059

0.810

 Future perspective (n = 25)

0.081

0.714

0.189

0.365

−0.276

0.214

−0.024

0.931

 Sexual functioning (n = 29)

0.479

0.011

0.268

0.160

−0.143

0.486

0.353

0.127

 Sexual enjoyment (n = 24)

0.299

0.176

−0.049

0.821

0.091

0.694

0.005

0.985

Symptom scales

 Radiation-induced micturition (n = 29)

−0.263

0.186

0.015

0.937

−0.091

0.659

−0.411

0.072

 Chemotherapy side effects (n = 29)

0.183

0.361

0.004

0.982

−0.203

0.319

−0.344

0.137

 Gastrointestinal symptoms (n = 29)

−0.304

0.123

−0.232

0.226

0.025

0.904

0.185

0.435

 Sexual dysfunction of men (n = 11)

−0.087

0.812

−0.304

0.364

0.464

0.176

0.268

0.254

 Sexual dysfunction of women (n = 4)

0.775

0.225

−0.258

0.752

−0.577

0.423

0.232

0.325

 Defecation problems (n = 29)

−0.159

0.429

−0.163

0.398

0.424

0.031

0.242

0.304

 Weight loss (n = 29)

−0.146

0.468

−0.021

0.913

0.445

0.023

0.00

1.00

  1. MSP Maximal squeeze pressure, RST Rectal sensory threshold, MBDV Minimal balloon distension volume, RAIR Rectoanal inhibitory reflex, r Correlation coefficient
  2. Spearman correlation analysis. Bold values indicate statistical significance at α=0.05 level