Table 2 Univariate analyses of the impact of prognostic factors on overall survival (OS) and progression free survival (PFS)
OS | PFS | |||
|---|---|---|---|---|
All patients | All patients | |||
HR (95 % CI) | p-value | Factors | HR (95 % CI) | p-value |
0.991 (0.981-1.001) | 0.089 | Interval surgery → RCT | 0.994 (0.985-1.003) | 0.188 |
1.017 (0.985-1.049) | 0.303 | Radiation treatment time | 1.008 (0.978-1.039) | 0.616 |
0.994 (0.985-1.003) | 0.198 | Overall duration of treatment | 0.995 (0.987-1.004) | 0.277 |
1.037 (1.026-1.048) | <0.001 | Age | 1.025 (1.016-1.035) | <0.001 |
1.389 (1.062-1.816) | 0.016 | ECOG state ≤ 1 vs > 1 | 1.241 (0.957-1.610) | 0.104 |
1.768 (1.397-2.236) | <0.001 | RPA-class ≤ 4 vs > 4 | 1.650 (1.315-2.070) | <0.001 |
1.825 (1.440-2.314) | <0.001 | Resection status (total vs. subtotal) | 1.560 (1.248-1.951) | <0.001 |
0.604 (0.474-0.769) | <0.001 | Simultaneous CT | 0.669 (0.528-0.848) | 0.001 |
0.888 (0.703-1.122) | 0.321 | Fractionation | 1.002 (0.806-1.246) | 0.984 |
0.312 (0.120-0.813) | 0.017 | MGMT methylation | 0.447 (0.220-0.909) | 0.026 |