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Fig. 2 | Radiation Oncology

Fig. 2

From: Targeting anti-apoptotic Bcl-2 by AT-101 to increase radiation efficacy: data from in vitro and clinical pharmacokinetic studies in head and neck cancer

Fig. 2

Dose- and time-dependent induction of apoptosis by radiation (a,c) and AT-101 (b,d) in HNSCC cell lines UM-SCC-11B (a,b) and VU-SCC-OE (c,d). Apoptosis was quantified 72 h after radiation and 48 h after exposure to AT-101. Data represent mean values ± SEM of an average of 11 independent experiments, performed in duplicate. Inserts show the time-dependency of radiation- and AT-101-induced apoptosis at the indicated doses

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