Fig. 2From: Targeting anti-apoptotic Bcl-2 by AT-101 to increase radiation efficacy: data from in vitro and clinical pharmacokinetic studies in head and neck cancerDose- and time-dependent induction of apoptosis by radiation (a,c) and AT-101 (b,d) in HNSCC cell lines UM-SCC-11B (a,b) and VU-SCC-OE (c,d). Apoptosis was quantified 72 h after radiation and 48 h after exposure to AT-101. Data represent mean values ± SEM of an average of 11 independent experiments, performed in duplicate. Inserts show the time-dependency of radiation- and AT-101-induced apoptosis at the indicated dosesBack to article page