study | No. of patients | Follow-up (years) | Age | Treatment | Local Recurrence rate |
P
|
|---|
ELIOT [7] | 1305 | 5.8 | 48-75 | IORT | 4.4 % | <.0001 |
| | | | | WBI | 0.4 % | |
TARGIT-A [11] | 1222 | 5 | >45 | IORT | 3.3 % | .042 |
| | | | | WBI | 1.3 % | |
PRIME II [13] | 1326 | 5 | >65 | Tam or AI | 4.1 % | .0002 |
| | | | | Tam or AI + RT | 1.3 % | |
CALGB9343 [14] | 636 | 12.6 | >70 | Tam | 10 % | <.001 |
| | | | | TamRT | 2 % | |
-
p, statistical significance; IORT, intraoperative radiotherapy; WBI, whole breast irradiation; Tam, tamoxifen; AI, aromatase inhibitor; RT, radiotherapy; TamRT, tamoxifen plus radiation therapy
