Skip to main content

Advertisement

Fig. 4 | Radiation Oncology

Fig. 4

From: A proliferation saturation index to predict radiation response and personalize radiotherapy fractionation

Fig. 4

In silico comparison of altered fractionation regimes using parameters estimated for NSCLC patients. a Model predicted improvement in tumor volume reduction when comparing (1.2 Gy x 58; b.i.d. 9 am and 3 pm; BED=73.8 Gy) RTOG phase III hyperfractionation [36] to the standard of care (2 Gy x 30; q.d. 9 am; BED=66 Gy) as a function of proliferation saturation index (PSI). Red line at 5 % indicates statistical significance. b Model predicted improved tumor volume reduction when comparing (1.2 Gy x 58; b.i.d. 9 am and 3 pm) hyperfractionation to the daily doses with equal BED (2.21 Gy x 30; q.d. 9 am; BED=73.8 Gy) as a function of proliferation saturation index (PSI)

Back to article page