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Fig. 2 | Radiation Oncology

Fig. 2

From: VE-821, an ATR inhibitor, causes radiosensitization in human tumor cells irradiated with high LET radiation

Fig. 2

VE-821 abrogated carbon ion-induced G2/M cell cycle arrest in tumor cells. HeLa and U2OS cells were pre-treated with 1 μM VE-821 or DMSO for 1 hour before irradiation, and were irradiated with 3 Gy of carbon ions or 6 Gy of X-rays. a Cells were harvested at 12 and 24 hours after irradiation and their cell cycle distributions were analyzed by flow cytometry. b The number of cells was counted immediately after and 1 day after irradiation. The relative cell number was calculated as follows: cell number after 1 day was divided by cell number immediately after irradiation. Error bars represent SEM of at least three independent experiments

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Radiation Oncology

ISSN: 1748-717X

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