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Table 3 The OARs low dose multi-comparison analysis for all studied techniques (mean ± SD). Mean values with ǂ symbol demonstrate that the corresponding technique did not pass the normality test. Friedman test of significance (p < 0.05) was used in these cases; otherwise, repeated measures ANOVA significance test was used

From: Comparison of breast simultaneous integrated boost (SIB) radiotherapy techniques

N = 12

 

T-2F

T-NC

T-VMAT

f-VMAT

ILung

V 5 (%)

32.0 ± 5.4c

37.9 ± 5.2bc

35.1 ± 4.6b

52.1 ± 6.3a

 

V 10 (%)

20.8 ± 4.5b

21.0 ± 4.1b

21.9 ± 3.9ǂ b

25.0 ± 2.7ǂ a

Heart (Lt.)

V 5 (%)

6.9 ± 3.4b

7.7 ± 3.3b

10.9 ± 5.0b

22.0 ± 5.6a

 

V 10 (%)

3.3 ± 2.6a

2.6 ± 1.9a

3.6 ± 2.2ǂ a

3.3 ± 1.6a

Heart (Rt.)

V 5 (%)

0.5 ± 0.3a

0.5 ± 0.9ǂ a

1.5 ± 1.5a

0.7 ± 0.7a

 

V 10 (%)

0* a

0* a

0* a

0* a

CBreast

V 5 (%)

0.5 ± 0.7ab

0.0 ± 0.1ǂ b

0.4 ± 0.5ǂ a

0.6 ± 0.8 a

 

V 10 (%)

0* a

0* a

0* a

0* a

CLung

V 5 (%)

0.2 ± 0.5ǂ ab

0.0 ± 0.0ǂ b

0.1 ± 0.3ǂ ab

0.4 ± 0.5ǂ a

 

V 10 (%)

0* a

0* a

0* a

0* a

  1. a,b,c,d Values having the same superscript in the same horizontal line are not significantly different
  2. V5 and V10 are volumes receiving 5 Gy and 10 Gy respectively