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Table 1 The targets coverage multi-comparison analysis for all studied techniques (mean ± SD). Mean values with ǂ symbol demonstrate that the corresponding technique did not pass the normality test. Friedman test of significance (p < 0.05) was used in these cases; otherwise, repeated measures ANOVA significance test was used

From: Comparison of breast simultaneous integrated boost (SIB) radiotherapy techniques

N = 12

 

T-2F

T-NC

T-VMAT

f-VMAT

PTV boost

V 107 (%)

0* a

0* a

0* a

0* a

 

V 95 (%)

95.9 ± 2.4c

98.0 ± 0.9ǂ bc

99.3 ± 0.6a

98.6 ± 1.7ab

 

mean (Gy)

64.1 ± 0.1b

64.2 ± 0.0b

64.3 ± 0.0a

64.1 ± 0.1b

 

CI

0.50 ± 0.00a

0.50 ± 0.00a

0.50 ± 0.00a

0.50 ± 0.00a

 

HI

1.03 ± 0.01† a

1.03 ± 0.01† a

1.03 ± 0.01† a

1.02 ± 0.01† b

PTV breast

V 107 (%)

18.1 ± 3.9a

18.7 ± 7.1ǂ a

18.7 ± 4.2a

10.4 ± 1.3b

 

V 95 (%)

94.5 ± 1.8b

94.6 ± 1.9ab

95.5 ± 2.3ab

96.6 ± 1.6a

 

mean (Gy)

52.2 ± 0.3a

52.2 ± 0.5ǂ a

52.3 ± 0.5a

51.5 ± 0.2b

 

Q

0.91 ± 0.02b

0.91 ± 0.02b

0.92 ± 0.03ab

0.94 ± 0.02a

 

hI

1.36 ± 0.03† a

1.37 ± 0.04† a

1.34 ± 0.05† a

1.30 ± 0.03† b

  1. a,b,c Values having the same superscript in the same horizontal line are not significantly different.
  2. *All the 12 patients have a 0 value.
  3. †Note that although these values look similar and have a comparatively small SD (between patients), the differences are significant due to individual patient’s variability (i.e. when looking at the paired data)
  4. V107 and V95 are volumes receiving 107 % and 95 % of prescribed dose respectively; CI, conformity index as defined by equation (1); HI, homogeneity index as defined by equation (2); Q is the quality of coverage as defined by equation (3); hI, heterogeneity index as defined by equation (4)