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Table 2 Summary of intraparenchymal radiation necrosis

From: Intratumoral and peritumoral post-irradiation changes, but not viable tumor tissue, may respond to bevacizumab in previously irradiated meningiomas

Patients

Age (years old)

Gender

Tumor

Bevacizumab (cycles)

Lesion

Location

Radiotherapy

Bev from RT (month)

Response rate ( %)

Radiological assessment

Case 2

52

M

anaplastic

3

Necrosis 1

occipital

SRS 14Gy/ SRS 14Gy/ SRT 25.5Gy/BNCT

13

−100

Response

Case 3

76

F

atypical

6

Necrosis 2

parasagittal

SRT 24Gy/ BNCT

8

−65

Response

Case 5

69

F

grade I

3

Necrosis 3

parasagittal

SRS/ SRS

13

−76

Response

Case 6

46

F

anaplastic

6

Necrosis 4

frontal

EBRT 60Gy/ BNCT/BNCT

4

−51

Response