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Table 1 Effects of SHP-1 knockdown and overexpression in CNE-1 and CNE-2 cells on radiosensitivity parameters

From: Increased SHP-1 expression results in radioresistance, inhibition of cellular senescence, and cell cycle redistribution in nasopharyngeal carcinoma cells

Radiosensitivity parameters

CNE-1

CNE-1-empty vector

CNE-1- scramble shRNA

CNE-1- SHP-1-overexpression

CNE-1- SHP-1- shRNA

CNE-2

CNE-2- empty vector

CNE-2- scramble shRNA

CNE-2- SHP-1- overexpression

CNE-2- SHP-1- shRNA

SF2

0.75

0.78

0.78

0.82

0.56

0.62

0.60

0.61

0.74

0.55

D0

2.51

2.38

2.38

2.85

2.17

1.94

1.80

1.94

2.08

1.50

Dq

1.77

1.85

1.85

1.96

1.26

1.46

1.43

1.43

1.75

1.36

N

2.34

2.68

2.65

2.48

1.62

2.22

2.32

2.17

2.77

2.58

  1. Note : SF2: cell survival fraction with 2 cGy irradiation dose; D0: mean lethal dose value; Dq: quasithreshold dose; N: extrapolation number