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Table 1 Effects of SHP-1 knockdown and overexpression in CNE-1 and CNE-2 cells on radiosensitivity parameters

From: Increased SHP-1 expression results in radioresistance, inhibition of cellular senescence, and cell cycle redistribution in nasopharyngeal carcinoma cells

Radiosensitivity parameters CNE-1 CNE-1-empty vector CNE-1- scramble shRNA CNE-1- SHP-1-overexpression CNE-1- SHP-1- shRNA CNE-2 CNE-2- empty vector CNE-2- scramble shRNA CNE-2- SHP-1- overexpression CNE-2- SHP-1- shRNA
SF2 0.75 0.78 0.78 0.82 0.56 0.62 0.60 0.61 0.74 0.55
D0 2.51 2.38 2.38 2.85 2.17 1.94 1.80 1.94 2.08 1.50
Dq 1.77 1.85 1.85 1.96 1.26 1.46 1.43 1.43 1.75 1.36
N 2.34 2.68 2.65 2.48 1.62 2.22 2.32 2.17 2.77 2.58
  1. Note : SF2: cell survival fraction with 2 cGy irradiation dose; D0: mean lethal dose value; Dq: quasithreshold dose; N: extrapolation number