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Fig. 4 | Radiation Oncology

Fig. 4

From: Increased SHP-1 expression results in radioresistance, inhibition of cellular senescence, and cell cycle redistribution in nasopharyngeal carcinoma cells

Fig. 4

Effects of SHP-1 knockdown in CNE-1 cells and overexpression in CNE-2 cells on cell cycle distribution and cell cycle-related protein (CDK4, Cyclin D1 and Cyclin E) expressions. a Cell cycle was determined by flow cytometry using propidium iodide staining three days after transduction. b BrdU incorporation assay to monitor S phase progression (magnification: ×200). c Cell cycle-related protein expressions were determined by western blot. β-actin was used as an inner control. Data are shown as mean ± SD. *P < 0.05, ** P < 0.01, *** P < 0.001 vs. CNE-1 or CNE-2; ## P < 0.01, ### P < 0.001 vs. CNE-1- scramble shRNA or CNE-2-empty vector

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Radiation Oncology

ISSN: 1748-717X

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