Fig. 3From: High levels of X-linked Inhibitor-of-Apoptosis Protein (XIAP) are indicative of radio chemotherapy resistance in rectal cancerXIAP expression increases in tumour tissue during radio chemotherapy. For 8 patients where pre-treatment biopsy and matched post-treatment surgical resection tissue was available the expression levels of XIAP in tumour and matched normal tissue were once again determined by quantitative Western blotting. a In individual patients, all but one patient had increased XIAP levels in resection tumour tissue, compared to matched tumour biopsy tissue, and XIAP expression was significantly increased in post treatment resection tumour tissue, when compared to pre-treatment biopsy tumour tissue (p = 0.004662). b In matched normal tissue 6 out of 8 patients had increased XIAP levels in resection tumour tissue, compared to matched tumour biopsy tissue. This trend was not significantBack to article page