Table 2 Radiation doses to cardiac structures in patients with hscTnT increase >30 % from baseline during RT (Group A) vs. patients without hscTnT increase (Group B)
Cardiac structure | Group A (N = 12) | Group B (N = 46) | p value* |
|---|---|---|---|
Heart | |||
Dmean (Gy) | 4.0 ± 1.8 | 2.8 ± 1.3 | 0.02 |
Dmax (Gy) | 48.9 ± 5.3 | 43.9 ± 11.0 | 0.13 |
V5 (%) | 12.0 ± 6.2 | 8.1 ± 4.6 | 0.02 |
V10 (%) | 8.4 ± 5.1 | 4.9 ± 3.4 | 0.01 |
V15 (%) | 7.1 ± 4.4 | 4.0 ± 3.1 | 0.01 |
V20 (%) | 5.7 ± 3.3 | 3.5 ± 2.8 | 0.02 |
V30 (%) | 4.0 ± 2.6 | 2.6 ± 2.3 | 0.08 |
AUC (%.Gy) | 403 ± 172 | 291 ± 134 | 0.02 |
LV | |||
Dmean (Gy) | 6.7 ± 3.3 | 4.5 ± 2.6 | 0.02 |
Dmax (Gy) | 47.8 ± 5.8 | 41.0 ± 12.2 | 0.07 |
V5 (%) | 22.0 ± 12.3 | 14.5 ± 9.2 | 0.02 |
V10 (%) | 15.5 ± 10.2 | 8.6 ± 7.0 | 0.01 |
V15 (%) | 13.2 ± 9.2 | 7.2 ± 6.4 | 0.01 |
V20 (%) | 11.1 ± 7.7 | 6.2 ± 5.9 | 0.02 |
V30 (%) | 7.1 ± 5.4 | 4.4 ± 4.7 | 0.10 |
AUC (%.Gy) | 668 ± 333 | 468 ± 260 | 0.03 |
LAD | |||
Dmean (Gy) | 23.8 ± 10.1 | 17.5 ± 10.8 | 0.07 |
Dmax (Gy) | 43.4 ± 11.8 | 37.9 ± 15.8 | 0.27 |
V5 (%) | 68.3 ± 24.2 | 61.7 ± 24.1 | 0.40 |
V10 (%) | 61.9 ± 26.1 | 45.7 ± 27.7 | 0.07 |
V15 (%) | 58.6 ± 26.3 | 40.0 ± 28.0 | 0.047 |
V20 (%) | 55.4 ± 26.3 | 36.2 ± 28.3 | 0.04 |
V30 (%) | 45.0 ± 25.3 | 29.3 ± 27.8 | 0.08 |
AUC (%.Gy) | 2422 ± 1053 | 1793 ± 1097 | 0.08 |