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Table 1 Demographic data of 166 cervical cancer patients requiring surgery for chronic radiation enteropathy

From: Clinical features, outcome and risk factors in cervical cancer patients after surgery for chronic radiation enteropathy

Characteristics

RRT (n = 46)

RS + RT (n = 120)

P value

Age, y (mean ± SD)

51.8 ± 10.4

47.8 ± 9.4

0.020

Tumor stage, n (%)a

  

0.000

 I-IIa

3(7.1)

78(86.7)

 

 IIB-IVa

39(92.9)

12(13.3)

 

Cumulative dosage, Gy (mean ± SD)b

72.6 ± 22.0

50.4 ± 13.1

0.000

 Preoperative, n (%)

-

5 (4.17)

 

 Postoperative, n (%)

-

111 (92.5)

 

 Pre/postoperative, n (%)

-

4 (3.33)

 

Chemotherapy, n (%)

26(56.5)

57(47.5)

0.298

Pathological pattern, n (%)c

  

0.147

 squamous carcinoma

40 (90.9)

94 (79.7)

 

 adenocarcinoma

4 (9.1)

14 (20.3)

 

Acute radiation enteritis, n (%)d

16/38 (42.1 %)

42/112(37.5 %)

0.614

Median latency period, n (%) Median (range), n (%)

9(3–264)

6(3–129)

0.000

 ≦6

13 (28.3)

70 (58.3)

0.001

 7–12

17 (37.0)

33 (27.5)

0.235

 13–24

6 (13.0)

7 (5.8)

0.122

 >24

10 (21.7)

10 (8.3)

0.018

Time interval from disease onset to referral Median (range)

6.5(1–108)

5.5(0.5–152)

0.295

BMI, mean ± SD (range) N (%)

19.0 ± 3.1

17.8 ± 3.2

0.025

 <=18.5

23(50.0)

75(65.8)

0.074

 >18.5

23(50.0)

39(34.2)

0.074

hypertension

3 (6.5)

9 (7.5)

1.000

Diabetes mellitus

2(4.3)

2(1.7)

0.658

Double j-tube placement, n (%)

4 (8.7)

1 (0.8)

0.021

Blood infusion, n (%)

9 (19.6)

29 (24.2)

0.528

Previous abdominal surgery, n (%)

21(45.7)

36(30.0)

0.086

  1. RRT Radical Radiotherapy, RS + RT Radical Surgery plus Radiotherapy, SD standard deviation, BMI body mass index
  2. aFIGO tumor stage was unknown in 34 patients (4/30)
  3. bRadiation dose was unknown in 39 patients (11/28)
  4. cPathological pattern was unknown in 14 patients (2/12)
  5. dAcute radiation enteritis was unknown in 16 patients (8/8)