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Table 1 Factors associated with the presence of microextension

From: Microinvasion of liver metastases from colorectal cancer: predictive factors and application for determining clinical target volume

Clinicopathological factor

n

Microextension, n (%)

x 2

P-value*

Absent

Present

Sex

   

0.790

0.598

Male

75

28 (37.3 %)

47 (62.7 %)

  

Female

54

20 (37.0 %)

34 (63.0 %)

  

Age

   

0.794

0.624

<65 years

93

34 (36.6 %)

59 (63.4 %)

  

≥65 years

36

14 (38.9 %)

22 (61.1 %)

  

Synchronous or metachronous

  

0.982

0.965

Synchronous

70

25 (35.7 %)

45 (64.3 %)

  

Metachronous

59

23 (39 %)

36 (61 %)

  

Original site

   

3.185

0.009

Rectum

48

25 (52.1 %)

23 (47.9 %)

  

Colon

81

23 (28.4 %)

58 (71.6 %)

  

Number of tumors

   

2.537

0.045

1

85

38 (44.7 %)

47 (55.3 %)

  

>1

44

10 (22.7 %)

34 (77.3 %)

  

Max tumor diameter

  

1.345

0.52

<3 cm

39

17 (43.6 %)

22 (56.4 %)

  

≥3 cm

90

31 (34.4 %)

59 (65.6 %)

  

CEA (ng/ml)

   

4.805

0.001

≤5

35

20 (57.1 %)

15 (42.9 %)

  

>5

94

28 (29.8 %)

66 (70.2 %)

  

CA199 (U/ml)

   

0.478

0.114

≤37

68

24 (35.3 %)

44 (64.7 %)

  

>37

61

24 (39.3 %)

37 (60.7 %)

  

Chemotherapy

   

0.906

0.817

Yes

55

21 (38.2 %)

34 (61.8 %)

  

No

74

27 (36.5 %)

47 (63.5 %)

  
  1. CEA Carcinoembryonic antigen, CA199 Carbohydrate antigen 19–9
  2. *Determined by binary logistic regression