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Table 1 Factors associated with the presence of microextension

From: Microinvasion of liver metastases from colorectal cancer: predictive factors and application for determining clinical target volume

Clinicopathological factor n Microextension, n (%) x 2 P-value*
Absent Present
Sex     0.790 0.598
Male 75 28 (37.3 %) 47 (62.7 %)   
Female 54 20 (37.0 %) 34 (63.0 %)   
Age     0.794 0.624
<65 years 93 34 (36.6 %) 59 (63.4 %)   
≥65 years 36 14 (38.9 %) 22 (61.1 %)   
Synchronous or metachronous    0.982 0.965
Synchronous 70 25 (35.7 %) 45 (64.3 %)   
Metachronous 59 23 (39 %) 36 (61 %)   
Original site     3.185 0.009
Rectum 48 25 (52.1 %) 23 (47.9 %)   
Colon 81 23 (28.4 %) 58 (71.6 %)   
Number of tumors     2.537 0.045
1 85 38 (44.7 %) 47 (55.3 %)   
>1 44 10 (22.7 %) 34 (77.3 %)   
Max tumor diameter    1.345 0.52
<3 cm 39 17 (43.6 %) 22 (56.4 %)   
≥3 cm 90 31 (34.4 %) 59 (65.6 %)   
CEA (ng/ml)     4.805 0.001
≤5 35 20 (57.1 %) 15 (42.9 %)   
>5 94 28 (29.8 %) 66 (70.2 %)   
CA199 (U/ml)     0.478 0.114
≤37 68 24 (35.3 %) 44 (64.7 %)   
>37 61 24 (39.3 %) 37 (60.7 %)   
Chemotherapy     0.906 0.817
Yes 55 21 (38.2 %) 34 (61.8 %)   
No 74 27 (36.5 %) 47 (63.5 %)   
  1. CEA Carcinoembryonic antigen, CA199 Carbohydrate antigen 19–9
  2. *Determined by binary logistic regression