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Fig. 5 | Radiation Oncology

Fig. 5

From: BRCC3 acts as a prognostic marker in nasopharyngeal carcinoma patients treated with radiotherapy and mediates radiation resistance in vitro

Fig. 5

BRCC3 knockdown intensifies G2/M checkpoint arrest. a Cell-cycle profiles of HNE1 and CNE2R cells. Control and BRCC3 siRNA transfected cells were treated with 0Gy or 4Gy, and the FACS analysis was executed 24 h post- irradiation.(nc: negative control siRNA; si1: siRNA1 target BRCC3; si2: siRNA2 target BRCC3). b Quantification of A. BRCC3 inhibition caused an increased portion of G2/M phase in HNE1 and CNE2R cells. c Western blot analysis of cyclinB1 24 h after 0Gy or 4Gy IR

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Radiation Oncology

ISSN: 1748-717X

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