Prognostic significance of clinical and pathological stages on locally advanced rectal carcinoma after neoadjuvant chemoradiotherapy

Table 3 Multivariate analysis of prognostic factors for patients with locally advanced rectal carcinoma

Variable	OS			DFS			LRFS			DMFS
Variable	HR	p value	95 % CI	HR	p value	95 % CI	HR	p value	95 % CI	HR	p value	95 % CI
pN stage
ypN+ vs. ypN0	2.206	0.016	1.159–4.196	2.239	0.004	1.286–3.898	2.239	0.003	1.286–3.898	2.678	0.004	1.374–5.218
pT stage
ypT3–4 vs. ypT0–2	2.640	0.007	1.308–5.331	1.441	0.175	0.850–2.443	1.621	0.121	0.880–2.987	2.196	0.027	1.096–4.400
Sex
Female vs. Male	0.859	0.663	0.433–1.702	0.861	0.605	0.487–1.522	0.794	0.486	0.414–1.520	0.924	0.824	0.461–1.853
Age, years
>56 vs. ≤56	1.382	0.298	0.752–2.539	1.389	0.208	0.833–2.315	1.679	0.081	0.939–3.004	1.683	0.107	0.894>–3.167

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