Table 3 Selected studies comparing local control as a function of BED

Van der Voort van Zyp et al. 2009 [19]

T1, n = 35; T2, n = 24

180 Gy

96 % at 2 years

n.s. p = 0.197

112. 5 Gy

78 % at 2 years

Onimaru et al. 2008 [20]

T1, n = 25; T2, n = 16

80 Gy

45 at 2 years

p = 0.0042

105.6 Gy

89 % at 2 years

Guckenberger et al. 2009 [21]

T1, n = 13; T2, n = 19; T3N0, n = 9

>100 Gy

89 % at 3 years

p = 0.0001

<100 Gy

62 % at 3 years

Bibault et al. 2012 [6]

T1, n = 31; T2, n = 20

≤150 Gy

70 % at 2 years

p = 0.006

>150 Gy

100 % at 2 years

Grills et al. 2012 [22]

T1, n = 318; T2, n = 67; T3, n = 10

<105 Gy

85 % at 2 years

p < 0.001

>105 Gy

96 % at 2 years

Onishi et al. 2007 [23]

Stage I, n = 257

>100 Gy

84 % at 3 years

p <0.01

<100 Gy

37 % at 3 years