Fig. 4
From: Medically inoperable peripheral lung cancer treated with stereotactic body radiation therapy
Comparing local control, disease free and overall survival rates in patients stratified by motion tracking system used during Cyberknife SBRT. Either a fiducial free (Xsight-spine/lung) or fiducial-based (Xsight-spine + fiducials) tracking system was used to localize and track tumors during each fraction of treatment. In the later technique, patients were initially aligned with Xsight-spine and then further adjusted through matching to intratumoral fiducials. a Overall Survival at 24 months was not statistically different in patients treated using Xsight-spine 69.2 % (95 % CL: 82.1-50.3 %) compared using Xsight-spine with fiducials 76.2 % (95 % CL: 88.6-58.0 %) (Logrank, p = 0.66) There was also no significant difference in b local control at 24 months for Xsight-spine alone 72.2 % (95 % CL: 94.8-49.6 %) vs. Xsight-spine with fiducials 52.3 % (95 % CL: 75.4-29.7 %) (Logrank, p = 0.44) or c disease free survival at 24 months when comparing Xsight-spine alone 51.4 % (95 % CL: 73.1-24.3 %) vs. Xsight-spine with fiducials, 52.3 % (95 % CL: 72.1-27.6 %) (Logrank, p = 0.97)