Radiation therapy improves survival in rectal small cell cancer - Analysis of Surveillance Epidemiology and End Results (SEER) data

Table 2 Cox Proportional Hazards Model with AJCC Stage as stratification variable

Variable	Level	No_RT N (%)	RT N (%)	Univariate HR	95% CI	P	Multivariate HR	95% CI	P
Radiation	No_RT	28 (100%)	N/A	Referent			Referent
	RT	N/A	43 (100%)	0.43	0.24 - 0.77	0.01	0.393	0.21 - 0.75	0.01
Surgery	No_Surgery	14 (32.6%)	29 (67.4%)	Referent			Referent
	Surgery	14 (50.0%)	14 (50.0%)	0.80	0.43 - 1.49	0.47	0.53	0.26 - 1.08	0.08
Sex	Male	16 (40.0%)	24 (60.0%)	Referent			Referent
	Female	12 (38.7%)	19 (61.3%)	0.91	0.49 - 1.70	0.76	0.90	0.47 - 1.74	0.76
Variable	Level	No_RT Mean (SD)	RT Mean (SD)	Univariate HR	95% CI	P	Multivariate HR	95% CI	P
Age at diagnosis	Continuous per year	62.4 (16.6)	58.9 (14.6)	1.02	1.0 - 1.04	0.14	1.01	0.98 - 1.03	0.32

Patients who received RT or no RT were subject to univariate and multivariate cox proportional hazards modeling (radiation, surgery, sex and age of diagnosis) with AJCC stage stratification.

ISSN: 1748-717X