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Table 3 Probabilities of radiation-induced rib fracture (n = 75)

From: Radiation-induced rib fracture after stereotactic body radiotherapy with a total dose of 54–56 Gy given in 9–7 fractions for patients with peripheral lung tumor: impact of maximum dose and fraction size

Categories

n

4y-rates (%)

p values

Age (y)

   

75

47

37.5

NS

<75

28

40.0

 

Sex

   

Male

50

32.7

NS

Female

25

47.2

 

Dmax (Gy)

   

54

55

47.7

0.0184

<54

20

12.9

 

Fraction size (Gy)

   

6

25

19.5

0.0458

7

23

31.2

 

8

27

55.7

 

PTV (cc)

   

50

28

41.2

NS

<50

47

35.5

 

Tumor location

   

Anterior

8

14.3

0.1097

Lateral

37

50.4

 

Posterior

30

27.1

 

Rib location

   

1–4

40

31.0

0.0738

5–8

35

42.1

 

9–12

6

75.0

 
  1. Abbreviations: Dmax = maximum dose of ribs; PTV = planning target volume; NS = not significant; HR = hazard ratio; CI = confidence interval.