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Table 3 Impact of potential prognostic factors on local control of MSCC (univariate analysis)

From: A matched-pair analysis comparing 5x4 Gy and 10x3 Gy for metastatic spinal cord compression (MSCC) in patients with favorable survival prognoses

 

At 6 months

At 12 months

P

RT regimen

   

 5 x 4 Gy (N = 142)

95

87

 

 10 x 3 Gy (N = 142)

98

93

0.16

Age

   

 ≤63 years (N = 142)

97

92

 

 ≥64 years (N = 142)

97

87

0.84

Gender

   

 Female (N = 138)

98

93

 

 Male (N = 146)

95

86

0.27

ECOG performance status

   

 1-2 (N = 226)

97

91

 

 3-4 (N = 58)

96

82

0.11

Type of primary tumor

   

 Breast cancer (N = 110)

99

93

 

 Prostate cancer (N = 76)

95

84

 

 Myeloma/lymphoma (N = 40)

100

95

 

 Lung cancer (N = 12)

100

100

 

 Other tumors (N = 46)

91

84

0.16

Involved vertebrae (N)

   

 1-2 (N = 134)

98

93

 

 ≥3 (N = 150)

96

87

0.09

Other bone metastases at the time of RT

   

 No (N = 140)

96

91

 

 Yes (N = 144)

97

88

0.53

Visceral metastases at the time of RT

   

 No (N = 264)

97

90

 

 Yes (N = 20)

100

80

0.32

Interval from tumor diagnosis to MESCC

   

 ≤15 months (N = 80)

97

97

 

 >15 months (N = 204)

97

88

0.24

Ambulatory status before RT

   

 Not ambulatory (N = 30)

96

71

 

 Ambulatory (N = 254)

97

91

0.027

Time developing motor deficits before RT

   

 1-7 days (N = 20)

78

78

 

 8-14 days (N = 68)

98

96

 

 >14 days (N = 196)

98

89

0.028