Table 2 Impact of potential prognostic factors on motor function
Radiotherapy successful | Radiotherapy not successful | P | |
|---|---|---|---|
N patients (%) | N patients (%) | ||
RT regimen | |||
5 x 4 Gy (N = 142) | 108 (76) | 34 (24) | |
10 x 3 Gy (N = 142) | 98 (69) | 44 (31) | 0.14 |
Age | |||
≤63 years (N = 142) | 104 (73) | 38 (27) | |
≥64 years (N = 142) | 102 (72) | 40 (28) | 0.77 |
Gender | |||
Female (N = 138) | 110 (80) | 28 (20) | |
Male (N = 146) | 96 (66) | 50 (34) | 0.51 |
ECOG performance status | |||
1-2 (N = 226) | 177 (78) | 49 (22) | |
3-4 (N = 58) | 29 (50) | 29 (50) | <0.001 |
Type of primary tumor | |||
Breast cancer (N = 110) | 93 (85) | 17 (15) | |
Prostate cancer (N = 76) | 51 (67) | 25 (33) | |
Myeloma/lymphoma (N = 40) | 29 (73) | 11 (27) | |
Lung cancer (N = 12) | 10 (83) | 2 (17) | |
Other tumors (N = 46) | 23 (50) | 23 (50) | <0.001 |
Involved vertebrae (N) | |||
1-2 (N = 134) | 95 (71) | 39 (29) | |
≥3 (N = 150) | 111 (74) | 39 (26) | 0.49 |
Other bone metastases at the time of RT | |||
No (N = 140) | 101 (72) | 39 (28) | |
Yes (N = 144) | 105 (73) | 39 (27) | 0.28 |
Visceral metastases at the time of RT | |||
No (N = 264) | 193 (73) | 71 (27) | |
Yes (N = 20) | 13 (65) | 7 (35) | 0.68 |
Interval from tumor diagnosis to MESCC | |||
≤15 months (N = 80) | 50 (63) | 30 (37) | |
>15 months (N = 204) | 156 (76) | 48 (24) | 0.12 |
Ambulatory status before RT | |||
Not ambulatory (N = 30) | 18 (60) | 12 (40) | |
Ambulatory (N = 254) | 188 (74) | 66 (26) | 0.47 |
Time developing motor deficits before RT | |||
1-7 days (N = 20) | 7 (35) | 13 (65) | |
8-14 days (N = 68) | 43 (63) | 25 (37) | |
>14 days (N = 196) | 156 (80) | 40 (20) | <0.001 |