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Table 2 Summary of DVH analysis

From: Which technique for radiation is most beneficial for patients with locally advanced cervical cancer? Intensity modulated proton therapy versus intensity modulated photon treatment, helical tomotherapy and volumetric arc therapy for primary radiation – an intraindividual comparison

Volume Pelvic RT EFRT
  HT IMPT IMRT VMAT HT IMPT IMRT VMAT
OAR Parameters
Bowel V 10Gy (%) 99.1 ± 1.3a,b,c 52.4 ± 15.8d,e 93.7 ± 4.1 94.6 ± 2.8 96.5 ± 4.3a 40.3 ± 7.1d,e 90.9 ± 6.6 94.0 ± 5.8
Bowel V 20Gy (%) 74.8 ± 12.6a,c 37.7 ± 13.3d,e 73.7 ± 12.0 74.2 ± 3.1 61.9 ± 1.4a,c 28.2 ± 7.0d,e 60.6 ± 9.3 59.8 ± 8.5
Bowel V 30Gy (%) 47.1 ± 18.8a,c 28.4 ± 10.6d,e 45.6 ± 12.9 44.8 ± 10.8 36.0 ± 10.6a,c 18.2 ± 5.5d,e 34.2 ± 8.5 32.7 ± 9.3
Bowel V 50Gy (%) 6.7 ± 3.6 5.6 ± 2.1d,e 11.8 ± 4.5 8.9 ± 2.5 6.5 ± 3.3a 2.9 ± 0.9d,e 8.8 ± 2.5 8.0 ± 2.8
Bowel D mean (Gy) 27.6 ± 5.6a 18.6 ± 5.9d,e 30.2 ± 4.0 34.1 ± 7.0 24.0 ± 4.1a 13.8 ± 2.8d,e 26.3 ± 3.2 25.3 ± 3.7
Rectum D mean (Gy) 47.8 ± 3.6a 41.4 ± 5.3e 47.2 ± 4.8 48.3 ± 1.6 48.2 ± 2.4a 41.3 ± 3.0d,e 48.5 ± 3.2 48.3 ± 1.5
Bladder D mean (Gy) 49.2 ± 1.4a 41.6 ± 5.8d,e 49.1 ± 3.4 50.1 ± 1.6 48.4 ± 2.8a 40.8 ± 6.4d,e 49.5 ± 3.8 48.9 ± 2.3
PTV Parameters
HI PTV_A 0.88 ± 0.02 0.87 ± 0.01 0.88 ± 0.01 0.87 ± 0.01 0.87 ± 0.01 0.87 ± 0.01 0.88 ± 0.01 0.88 ± 0.01
HI PTV_B 0.94 ± 0.01a,b 0.96 ± 0.01d,e 0.92 ± 0.01f 0.94 ± 0.01 0.94 ± 0.02a 0.96 ± 0.01d,e 0.93 ± 0.01 0.94 ± 0.01
CN PTV_A 0.88 ± 0.03a,b 0.92 ± 0.01d,e 0.82 ± 0.02f 0.88 ± 0.03 0.85 ± 0.13 0.88 ± 0.01d 0.82 ± 0.06 0.88 ± 0.03
CN PTV_B 0.87 ± 0.02 0.88 ± 0.05 0.84 ± 0.06 0.88 ± 0.03 0.86 ± 0.06a,c 0.89 ± 0.03d 0.78 ± 0.08 0.87 ± 0.08
CI PTV_A 1.09 ± 0.05a,b,c 1.03 ± 0.02d,e 1.20 ± 0.03f 0.98 ± 0.01 1.16 ± 0.07 1.05 ± 0.02d,e 1.22 ± 0.11f 0.97 ± 0.01
CI PTV_B 1.07 ± 0.06 1.08 ± 0.07 1.16 ± 0.09f 1.09 ± 0.05 1.15 ± 0.11 1.07 ± 0.06d 1.24 ± 0.13f 1.08 ± 0.10
  1. HI: homogeneity index; CN: conformality number; CI: conformality index. VxGy: volume receiving at least x Gy. HT: helical tomotherapy; IMPT: intensity modulated proton therapy; IMRT: intensity modulated radiation therapy; VMAT: volumetric modulated arc therapy. EFRT: extended field radiation therapy. Statistical significance when p < 0.05. aHT vs IMPT; bHT vs IMRT; cHT vs VMAT; dIMPT vs IMRT; eIMPT vs VMAT; fIMRT vs VMAT.